Transform AI readiness into operational impact for government

According to MIT’s latest report, “The GenAI Divide: State of AI in Business 2025,” while only a small percentage of AI projects successfully reach operations, this creates an important opportunity for government agencies to focus on developing strategies that translate executive AI mandates, pilot programs, and innovation budgets into measurable, scalable results. Any deployment that doesn’t have the right operational strategy will waste both time and money — and AI is no different. At the same time, delays in AI deployments mean first responders and federal teams will endure capability gaps.

That’s where Domino and NVIDIA can help. Together, Domino and NVIDIA bridge the gaps on the missing layer in between experimentation and execution. It’s about governed, secure infrastructure that turns a model into a system, and ultimately a system into an operational asset. Leveraging both Domino and NVIDIA, your AI teams can build, deploy, and trust AI systems that are ready for the real world.

Innovation with NVIDIA AI Factory for Government

The NVIDIA AI Factory for Government is a full-stack, end-to-end reference design that brings the power of reasoning AI to high-assurance organizations. It combines NVIDIA government-ready software containers, with GPU-accelerated infrastructure, a broad technology partner ecosystem and support for on-premises, hybrid, and air-gapped environments.

Domino plugs directly into this design, providing the orchestration layer that transforms the NVIDIA AI Factory reference architecture into an operational pipeline. Specifically, Domino enables federal teams to:

• Run and manage NVIDIA containers securely across IL5/6 environments
• Build, train, and deploy AI using reproducible, auditable workflows
• Govern every stage of the model lifecycle — from initial training to retraining and rollback
• Track model lineage, monitor performance, and detect drift in real time
• Support hybrid workloads, including AI/ML pipelines running on HPC clusters and GPU-accelerated systems

Together, Domino and NVIDIA give high-assurance organizations the speed of innovation and the certainty of control.

Empower mission-critical AI securely and responsibly

The challenges facing federal AI teams aren’t about modeling skill. They’re about getting models to the critical workloads — securely, responsibly, and repeatably.

Here’s what Domino delivers to AI teams:

• Reproducibility across training, testing, and deployment
• Portability across secure enclaves, cloud, and hybrid environments
• Auditability with full lineage tracking and version control
• Observability through built-in monitoring and drift detection
• Collaboration across data science, DevOps, and program leaders

Domino builds the connective tissue between AI research, engineering, and operations — so your models aren’t trapped in notebooks, but deployed where they matter.

How to enable agentic AI with HPC-scale performance

The next generation of AI systems won’t be monolithic. They’ll be multi-model, multi-role, and autonomous. This agentic architecture needs more than intelligence, they also need HPC-scale performance. Domino is built for both.

Domino enables you to build once, deploy securely, and govern continuously. AI teams will get models out of the lab and into the mission-critical workloads with both scientific exploration and operational rigor.

Looking ahead

With Domino and NVIDIA, the infrastructure is now in place: secure, repeatable, and aligned with the realities of intelligence and mission-critical operations. So, what’s next? At NVIDIA GTC DC, October 27–29, Domino will demonstrate how federal agencies are using the NVIDIA AI Factory for Government to move faster, with trust built in. Get ready to evolve your AI journey and turn AI readiness into operational impact.